Abandoned Clinical Trials Leave Patients Vulnerable

Fri Mar 14 2025 15:32:35 GMT+0200 (Eastern European Standard Time)
Abandoned Clinical Trials Leave Patients Vulnerable

A sudden halt in research due to a Trump administration order has critically endangered participants in clinical trials worldwide.


Thousands of individuals are left without vital medical oversight and support, raising serious ethical concerns.

Asanda Zondi was among many participants caught in the crossfire of a U.S. Agency for International Development (USAID) funding freeze, following an executive order by President Trump. Zondi, 22, was informed to attend a health clinic in Vulindlela, South Africa, to remove a silicone device intended for preventing pregnancy and HIV infection, only to discover that the ongoing clinical trial was abruptly shut down.

The decision to halt all USAID-funded research globally has left numerous participants in dire situations, as they are now deprived of necessary monitoring and care. Many individuals, like Zondi, have experimental medications or devices in their bodies and are isolated from researchers who would typically observe their progress.

Following the execution of the order, the State Department—which now supervises USAID—directed inquiries back to an official website that has been stripped of pertinent information aside from noting that all permanent employees are currently on administrative leave. Secretary of State Marco Rubio has labeled the agency as bureaucratically wasteful and misaligned with President Trump’s foreign policy objectives.

Leading scientists involved in these trials are caught in a moral bind, facing the heart-wrenching decision of whether to defy the order to safeguard their participants or remain compliant, potentially exposing them to unmonitored effects of the drugs and devices used in the trials. Concerns continue to mount over the ramifications of this abrupt shutdown, leaving communities with an alarming uncertainty regarding their health and safety.

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