The Legacy of James Harrison: The Man Who Saved Millions With His Blood

James Harrison, a legendary figure in the field of blood donations, has left a profound legacy after passing away at 88 on February 17. His remarkable journey as a plasma donor, characterized by over 1,173 donations, made a significant difference in the lives of approximately 2.4 million babies in Australia. Known for possessing a rare antibody called anti-D, Harrison's contributions were critical in developing a life-saving medication for pregnant women, thus helping avert potential health issues for mothers and their babies.

James Harrison was not fond of needles; he would turn his head away each time he donated plasma. Yet, for over six decades, he overcame this discomfort to become one of the most prolific blood donors in history, contributing 1,173 times. He was known as "The Man with the Golden Arm," an affectionate nickname that recognized his extraordinary contributions. Harrison passed away peacefully in a nursing home located about an hour from his regular donation center in Sydney, as confirmed by his grandson, Jarrod Mellowship, on March 4, 2025.

Harrison's plasma contained an exceptional antibody known as anti-D, which proved pivotal in creating a treatment for expectant mothers whose bodies might reject their unborn children due to differing blood types. Specifically, this occurs when a Rh-negative mother carries a Rh-positive fetus, which can lead to serious health complications for both. Thanks to his unwavering commitment to donate, Harrison's blood helped prevent serious diseases and saved countless lives, making him a national hero in Australia and earning him a place in the annals of medical history.