More than 35 people have been killed in Israeli strikes and gunfire since the early hours of Saturday morning, hospital sources in Gaza say.
A strike on a house in central Gaza left at least 11 people dead - more than half of them women and children - according to officials at al-Ahli Arab hospital in Gaza City.
Health workers said nine members of the same family were among those killed in an Israeli strike on the Nuseirat refugee camp, and at least six people are reported to have died while seeking aid in central and southern Gaza.
It comes a day after Israeli PM Benjamin Netanyahu told the United Nations that Israel must finish the job against Hamas.
The Israeli air force says it has hit approximately 120 targets across the Strip since Friday - including buildings used by terror groups, terror operatives and other infrastructure.
There has been no let up in Israel's recent expanded ground offensive against Hamas, which is now mainly focused on Gaza City, where Israel believes is the last stronghold of the armed group.
Hundreds of thousands have fled the territory's largest urban centre, which is experiencing a humanitarian crisis. Residents reported chaotic conditions, with one noting, They tell us go there, then come back here... Where should we go?
Calls for a ceasefire have increased, coinciding with multiple recognitions of Palestinian statehood at the UN. However, Israel maintains its focus on exerting pressure on Hamas for potential surrender.
This relentless military operation follows a Hamas-led attack on Israel on October 7, 2023, which resulted in approximately 1,200 fatalities. Israeli attacks in response have reportedly killed at least 65,549 people in Gaza since then.
The situation has pushed many to despair as they navigate a future filled with uncertainty and anguish. What does the world want from us? What does Netanyahu want? What does Hamas want? questioned a bewildered resident.
