Police activity connected to the search for Nancy Guthrie, the missing mother of US news anchor Savannah Guthrie, is under way at a residence about two miles from her home.

Armed police teams have been observed in the area, with a sheriff's vehicle blocking access.

This surge in police activity follows reports that investigators had found DNA at Guthrie's address that does not belong to her or anyone close to her.

The 84-year-old has been missing since she disappeared in the middle of the night from her home in Tucson, Arizona, nearly two weeks ago. Authorities suspect she may have been taken against her will.

In a social media update, the sheriff's department confirmed that law enforcement activity is ongoing concerning the Guthrie case but did not disclose further details.

Pima County Sheriff Chris Nanos indicated that investigators are actively working a lead. Over a dozen law enforcement vehicles, including SWAT teams and forensic units, have been seen in the vicinity.

Investigators have also found several gloves near the area, with the most recent discovery occurring about two miles from Nancy Guthrie's home. The sheriff's department clarified that reports of a glove being found inside her home are inaccurate, and all evidence has been forwarded for laboratory analysis.

The FBI has released a physical description of a suspect believed to be involved in the case. Following the release of doorbell camera footage, investigators received over 13,000 tips, amplifying the urgency surrounding the investigation.

As the search continues, the FBI has increased the reward for information regarding Guthrie's disappearance to $100,000. Family members have made emotional appeals on social media, expressing their belief that she is still alive and indicating they would be willing to pay for her safe return.